Generally, the most comfortable car cannot be pinpointed on one. The most comfortable cars on the road are the luxury cars which come with a higher price tag. There are six new cars that come under this category. They are LS 460L and ES350 models from Lexus, S-ClassS550, E-ClassE350 and GL-Class GL450 models from Mercedes-Benz and Cadillac DTS Luxury ll. Lexus LS 460L has an electronic controlled breaking (EBS) system and is fitted with a number of airbags. The ES350 model is the newest addition to the market. One of the key features of Mercedes-Benz cars is the air suspension system that can be adjusted. The latest DTS cars also have an EBS system and an excellent air suspension system.